Lambda variant vaccine: SARS-CoV-2 Lambda variant now in 29 countries, Delta vs Lambda variant which is the most dangerous: which is the most dangerous among Kovid’s delta and lambda variants, which the WHO has said

Different variants of the corona virus are wreaking havoc around the world. In many countries, including India, the Delta and Delta Plus variants have infected large numbers of people, while in many countries in South America and Europe, the Lambda variants have infected people. Birmingham City University Birmingham Tara Hurst in the UK has done a lot of research on the lambda variant. He explained in The Conversation how dangerous this variant is and in which countries it is affected.

Peru and Hungary lead in Corona lakh deaths
He said Peru has by far the highest number of Kovid deaths per capita. Out of 100,000 inhabitants, 596 died in Kovid. The second most affected country is Hungary, with 307 deaths per 100,000 inhabitants. There are many reasons why the epidemic in Peru is so high. These include a poorly funded and underdeveloped health system with too few intensive care beds; slow vaccination; limited testing capacity; a large informal economy (some people cannot work); and overcrowded housing.

The lambda variant is wreaking havoc in Peru
Peru also faced the lambda variant. Initially confirmed in the capital Lima in August 2020, in April 2021, its impact in Peru was 97%. Lambda is now universal. According to a recent report from the World Health Organization (WHO), it has been found in 29 countries. The report states that lambda is the cause of community transmission in many countries, with its prevalence and the number of COVID-19 patients increasing over time.

WHO calls global lambda variant
On June 14, 2021, the WHO declared lambda to be a global variant of the disease. On June 23, Public Health England dubbed it the variant under study because of its international expansion and several notable mutations. Most of the eight confirmed cases of Lambda in the UK have been linked to overseas travel.

as the evidence shows
A variant of viral curiosity is one that has mutations that affect things such as transmissibility (how easily the virus spreads), the severity of the disease, the ability to escape previous infections, or immunity. confusing vaccines, or diagnostic tests. Many scientists are talking about an unusual combination of lambda mutations, which could make it more transmissible.

Why is the lambda variant dangerous?
lambda has seven mutations on the spike protein, the fungus-like structure on the virus’s outer shell, that help it attach and invade our cells. These mutations can facilitate the binding of lambda to our cells and make it more difficult for our antibodies to capture and neutralize the virus.

But it’s important to remember that neutralizing antibodies aren’t the only tool in the immune system’s toolkit, they’re the easiest to study. T cells also play an important role, so a handful of mutations – although rare – may not be enough to cause lambda to escape our immune system altogether.

Very lack of information on lambda
So what evidence do we have that these mutations make lambda more dangerous than the original corona virus? Very little, it turns out. There are no published studies on the lambda version and only a handful of preprints that have yet to be studied by other scientists (peer review) and published in a journal.

This vaccine is effective against lambda
A preprint from the Grossman School of Medicine at New York University examined the effects of Pfizer and Moderna vaccines against lambda variants and found a two to three-fold reduction in vaccine-derived antibodies compared to the original virus . Analysis of this is not a major drawback of neutralizing antibodies. The researchers concluded that these mRNA vaccines would likely remain protective against the lambda variant.

Chinese vaccine failed against Lambda
Researchers at the University of Chile studied the effect of the Sinovac vaccine (also known as CoronaVac) against a lambda variant. They found a three-fold reduction in neutralizing antibodies compared to the original version. The fact that these two studies found partial inactivation is not minor but significant, as it is only one aspect of the immune response induced by vaccination.

Lambda still far behind Delta
According to Lambda’s latest PHE risk assessment (July 8), there is no evidence of a country where Lambda has outperformed Delta. Studies are ongoing, but for now, the lambda remains a type of curiosity rather than a type of concern.

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